STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (348 aa)    
Predicted Functional Partners:
Malapachy_1221
Ubiquinone biosynthesis hydrox.
 
 
 0.977
COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
   
 0.966
Malapachy_1651
Sec1-like protein; Belongs to the STXBP/unc-18/SEC1 family.
 
      0.729
Malapachy_3451
Abc1-ubiquinol--cytochrome-c reductase complex assembly protein.
   
 0.707
Malapachy_3488
Oxidoreductase-like domain-containing protein.
   
 0.707
Malapachy_0335
Abc1-domain-containing protein.
    
 0.696
Malapachy_1474
L-serine dehydratase.
   
 0.673
Malapachy_2972
Atypical abc1 abc1-c protein kinase.
    
 0.673
Malapachy_1995
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
   
 0.669
Malapachy_0530
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
  
 0.647
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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