STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_1721Ankyrin repeat containing protein. (1377 aa)    
Predicted Functional Partners:
Malapachy_1075
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 0.830
Malapachy_2073
Cullin-domain-containing protein; Belongs to the cullin family.
    
 0.788
Malapachy_2157
Scf complex member cullin 1; Belongs to the cullin family.
    
 0.747
Malapachy_0797
Histone H2A; Belongs to the histone H2A family.
    
 0.723
Malapachy_1925
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.706
Malapachy_0069
Essential component of the nuclear pore which mediates nuclear import and export.
   
 0.700
Malapachy_2010
RanBD1 domain-containing protein.
   
 0.700
Malapachy_3680
Essential component of the nuclear pore which mediates nuclear import and export.
   
 0.700
Malapachy_3683
Transcription factor.
    
 0.694
Malapachy_3722
Ankyrin repeat protein.
    
 0.692
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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