Malapachy_2238 protein (Malassezia pachydermatis)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Malapachy_2238

Protein phosphatase. (531 aa)

Predicted Functional Partners:

Malapachy_0376

0.867

Malapachy_1356

0.805

Malapachy_1996

0.789

Malapachy_1201

0.777

Malapachy_0086

0.774

Malapachy_2845

0.764

Malapachy_1226

0.764

Malapachy_1776

0.764

Malapachy_0181

0.743

Malapachy_3383

0.740

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Malapachy_0086	Malapachy_1996	A0A0M9VNJ1	A0A0M8MNU1	Nadh-ubiquinone oxidoreductase kDa subunit.	Tim17-domain-containing protein.	0.992
Malapachy_0086	Malapachy_2238	A0A0M9VNJ1	A0A0M8MWN0	Nadh-ubiquinone oxidoreductase kDa subunit.	Protein phosphatase.	0.774
Malapachy_0181	Malapachy_0376	A0A0M9VNI9	A0A0M9VMV2	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	Transcription factor tfiif complex alpha subunit tfg1.	0.999
Malapachy_0181	Malapachy_1201	A0A0M9VNI9	A0A0M8MML3	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	Rna polymerase ii subunit.	0.988
Malapachy_0181	Malapachy_1226	A0A0M9VNI9	A0A0M8MKU1	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.995
Malapachy_0181	Malapachy_1776	A0A0M9VNI9	A0A0M8MSX8	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	Nitroreductase family protein.	0.880
Malapachy_0181	Malapachy_2238	A0A0M9VNI9	A0A0M8MWN0	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	Protein phosphatase.	0.743
Malapachy_0181	Malapachy_2845	A0A0M9VNI9	A0A0M8MJ37	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	Uncharacterized protein.	0.880
Malapachy_0181	Malapachy_3383	A0A0M9VNI9	A0A0M8MYW3	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	Rpc40-40 kd subunit of dna-directed rna polymerases i and iii.	0.936
Malapachy_0376	Malapachy_0181	A0A0M9VMV2	A0A0M9VNI9	Transcription factor tfiif complex alpha subunit tfg1.	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	0.999
Malapachy_0376	Malapachy_1201	A0A0M9VMV2	A0A0M8MML3	Transcription factor tfiif complex alpha subunit tfg1.	Rna polymerase ii subunit.	0.987
Malapachy_0376	Malapachy_1226	A0A0M9VMV2	A0A0M8MKU1	Transcription factor tfiif complex alpha subunit tfg1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.973
Malapachy_0376	Malapachy_1776	A0A0M9VMV2	A0A0M8MSX8	Transcription factor tfiif complex alpha subunit tfg1.	Nitroreductase family protein.	0.880
Malapachy_0376	Malapachy_2238	A0A0M9VMV2	A0A0M8MWN0	Transcription factor tfiif complex alpha subunit tfg1.	Protein phosphatase.	0.867
Malapachy_0376	Malapachy_2845	A0A0M9VMV2	A0A0M8MJ37	Transcription factor tfiif complex alpha subunit tfg1.	Uncharacterized protein.	0.880
Malapachy_0376	Malapachy_3383	A0A0M9VMV2	A0A0M8MYW3	Transcription factor tfiif complex alpha subunit tfg1.	Rpc40-40 kd subunit of dna-directed rna polymerases i and iii.	0.931
Malapachy_1201	Malapachy_0181	A0A0M8MML3	A0A0M9VNI9	Rna polymerase ii subunit.	Tfg2-tfiif subunit (Transcription initiation factor) 54 kd.	0.988
Malapachy_1201	Malapachy_0376	A0A0M8MML3	A0A0M9VMV2	Rna polymerase ii subunit.	Transcription factor tfiif complex alpha subunit tfg1.	0.987
Malapachy_1201	Malapachy_1226	A0A0M8MML3	A0A0M8MKU1	Rna polymerase ii subunit.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
Malapachy_1201	Malapachy_1776	A0A0M8MML3	A0A0M8MSX8	Rna polymerase ii subunit.	Nitroreductase family protein.	0.906

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Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.838

expected number of edges:

28

PPI enrichment p-value:

0.0102

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

4 of 55

1.41

0.88

0.0102

GO:0019843

rRNA binding

3 of 42

1.4

0.64

0.0459

GO:0003723

RNA binding

4 of 110

1.11

0.56

0.0459

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022625

Cytosolic large ribosomal subunit

4 of 23

1.78

1.88

7.73e-05

GO:0032991

Protein-containing complex

5 of 227

0.89

0.67

0.0036

GO:0005829

Cytosol

5 of 312

0.75

0.51

0.0117

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:26617599

(2015) Comparative Genomic Insights into Ecophysiology of Neutrophilic, Microaerophilic Iron Oxidizing Bacteria.

3 of 16

1.82

0.98

0.0117

PMID:28083017

(2016) Distribution of Hydrogenases in Cyanobacteria: A Phylum-Wide Genomic Survey.

3 of 19

1.74

0.97

0.0117

PMID:36545193

(2022) Characterizing corn-straw-degrading actinomycetes and evaluating application efficiency in straw-returning experiments.

3 of 29

1.56

0.83

0.0195

PMID:21936919

(2011) Genomic insights into an obligate epibiotic bacterial predator: Micavibrio aeruginosavorus ARL-13.

3 of 32

1.52

0.82

0.0195

PMID:19148287

(2009) Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum.

3 of 31

1.53

0.82

0.0195

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1368

HotDog domain superfamily, and Epoxide hydrolase-like

3 of 6

2.24

1.84

0.00030

CL:1322

Mixed, incl. Lipid oxidation, and Acyl-CoA dehydrogenase, middle domain

4 of 29

1.68

1.59

0.00030

CL:1250

Mixed, incl. Fatty acid metabolic process, and Carbon fixation pathways in prokaryotes

6 of 93

1.35

1.43

8.61e-05

CL:1252

Carbon fixation pathways in prokaryotes, and Fatty acid metabolic process

5 of 64

1.44

1.39

0.00028

CL:148

Cytosolic large ribosomal subunit, and Small ribosomal subunit

3 of 23

1.66

1.1

0.0050

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cau03010

Ribosome

4 of 55

1.41

1.15

0.0016

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0036125

Fatty acid beta-oxidation multienzyme complex

2 of 5

2.15

0.76

0.0393

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 5

2.15

0.76

0.0393

GOCC:0005840

Ribosome

3 of 39

1.43

0.67

0.0393

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

4 of 53

1.42

1.09

0.0027

KW-0699

rRNA-binding

3 of 39

1.43

0.86

0.0130

KW-0276

Fatty acid metabolism

2 of 13

1.73

0.72

0.0398

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF16113

Enoyl-CoA hydratase/isomerase

3 of 7

2.18

1.53

0.0012

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