STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2480Acetoacetyl-synthetase. (914 aa)    
Predicted Functional Partners:
Malapachy_1103
3-hydroxyacyl-dehydrogenase.
  
 
 0.968
Malapachy_2780
Acetyl-c-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.966
Malapachy_1174
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.951
Malapachy_0772
Citrate synthase; Belongs to the citrate synthase family.
  
 0.923
Malapachy_0662
Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.836
Malapachy_2702
Malate synthase; Belongs to the malate synthase family.
   
 0.812
Malapachy_0722
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.802
Malapachy_2119
Malic enzyme.
  
 0.802
Malapachy_1417
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.802
Malapachy_2438
Urea transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.790
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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