node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Malapachy_0662 | Malapachy_0722 | A0A0M9VPM2 | A0A0M8MN82 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.803 |
Malapachy_0662 | Malapachy_0772 | A0A0M9VPM2 | A0A0M8MMZ8 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.882 |
Malapachy_0662 | Malapachy_1103 | A0A0M9VPM2 | A0A0M9VPV1 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxyacyl-dehydrogenase. | 0.997 |
Malapachy_0662 | Malapachy_1174 | A0A0M9VPM2 | A0A0M9VPR4 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.905 |
Malapachy_0662 | Malapachy_1417 | A0A0M9VPM2 | A0A0M9VN72 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.803 |
Malapachy_0662 | Malapachy_2480 | A0A0M9VPM2 | A0A0M8MWN7 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetoacetyl-synthetase. | 0.836 |
Malapachy_0662 | Malapachy_2702 | A0A0M9VPM2 | A0A0M9VQG9 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Malate synthase; Belongs to the malate synthase family. | 0.859 |
Malapachy_0662 | Malapachy_2780 | A0A0M9VPM2 | A0A0M8MHE8 | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetyl-c-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.973 |
Malapachy_0722 | Malapachy_0662 | A0A0M8MN82 | A0A0M9VPM2 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.803 |
Malapachy_0722 | Malapachy_0772 | A0A0M8MN82 | A0A0M8MMZ8 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Citrate synthase; Belongs to the citrate synthase family. | 0.564 |
Malapachy_0722 | Malapachy_1103 | A0A0M8MN82 | A0A0M9VPV1 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 3-hydroxyacyl-dehydrogenase. | 0.851 |
Malapachy_0722 | Malapachy_1174 | A0A0M8MN82 | A0A0M9VPR4 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.807 |
Malapachy_0722 | Malapachy_2480 | A0A0M8MN82 | A0A0M8MWN7 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acetoacetyl-synthetase. | 0.802 |
Malapachy_0722 | Malapachy_2780 | A0A0M8MN82 | A0A0M8MHE8 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acetyl-c-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.838 |
Malapachy_0772 | Malapachy_0662 | A0A0M8MMZ8 | A0A0M9VPM2 | Citrate synthase; Belongs to the citrate synthase family. | Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.882 |
Malapachy_0772 | Malapachy_0722 | A0A0M8MMZ8 | A0A0M8MN82 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.564 |
Malapachy_0772 | Malapachy_1103 | A0A0M8MMZ8 | A0A0M9VPV1 | Citrate synthase; Belongs to the citrate synthase family. | 3-hydroxyacyl-dehydrogenase. | 0.846 |
Malapachy_0772 | Malapachy_1174 | A0A0M8MMZ8 | A0A0M9VPR4 | Citrate synthase; Belongs to the citrate synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.907 |
Malapachy_0772 | Malapachy_1417 | A0A0M8MMZ8 | A0A0M9VN72 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.564 |
Malapachy_0772 | Malapachy_2119 | A0A0M8MMZ8 | A0A0M8MVY9 | Citrate synthase; Belongs to the citrate synthase family. | Malic enzyme. | 0.956 |