STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2560Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (981 aa)    
Predicted Functional Partners:
Malapachy_2452
POT1PC domain-containing protein.
    
 0.951
Malapachy_1066
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 
 0.891
Malapachy_0513
Uncharacterized protein.
   
 
 0.889
Malapachy_1829
Rrna pseudouridine synthase.
    
 0.875
Malapachy_2292
Spoc domain-like protein.
   
 
 0.860
Malapachy_2462
Ku70-like protein.
    
 
 0.859
Malapachy_1094
Rna-binding protein nhp2.
    
 0.820
Malapachy_4091
ATP-dependent DNA helicase; Belongs to the helicase family.
    
 0.816
Malapachy_1828
Pseudouridine synthase.
    
 0.805
Malapachy_2349
Uncharacterized protein.
   
 
 0.805
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.