| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FEN1 | Malapachy_0491 | A0A0M9VQ18 | A0A0M8MM31 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.551 |
| FEN1 | Malapachy_0762 | A0A0M9VQ18 | A0A0M9VPK8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Lymphoid-specific helicase-like protein. | 0.671 |
| FEN1 | Malapachy_1478 | A0A0M9VQ18 | A0A0M9VNF1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Transcription elongation factor. | 0.561 |
| FEN1 | Malapachy_2579 | A0A0M9VQ18 | A0A0M8MPD5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Small ubiquitin-related modifier. | 0.686 |
| FEN1 | Malapachy_3005 | A0A0M9VQ18 | A0A0M8MXW7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.505 |
| FEN1 | Malapachy_3342 | A0A0M9VQ18 | A0A0M9VRF6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Chromatin remodelling complex atpase chain isw1. | 0.680 |
| Malapachy_0110 | Malapachy_0704 | A0A0M9VNN3 | A0A0M9VPW4 | Ubiquitin-conjugating enzyme9; Belongs to the ubiquitin-conjugating enzyme family. | Aos1-smt3p activating protein. | 0.980 |
| Malapachy_0110 | Malapachy_0762 | A0A0M9VNN3 | A0A0M9VPK8 | Ubiquitin-conjugating enzyme9; Belongs to the ubiquitin-conjugating enzyme family. | Lymphoid-specific helicase-like protein. | 0.685 |
| Malapachy_0110 | Malapachy_2058 | A0A0M9VNN3 | A0A0M9VQF2 | Ubiquitin-conjugating enzyme9; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. | 0.996 |
| Malapachy_0110 | Malapachy_2579 | A0A0M9VNN3 | A0A0M8MPD5 | Ubiquitin-conjugating enzyme9; Belongs to the ubiquitin-conjugating enzyme family. | Small ubiquitin-related modifier. | 0.999 |
| Malapachy_0110 | Malapachy_3005 | A0A0M9VNN3 | A0A0M8MXW7 | Ubiquitin-conjugating enzyme9; Belongs to the ubiquitin-conjugating enzyme family. | Uncharacterized protein. | 0.921 |
| Malapachy_0110 | Malapachy_3342 | A0A0M9VNN3 | A0A0M9VRF6 | Ubiquitin-conjugating enzyme9; Belongs to the ubiquitin-conjugating enzyme family. | Chromatin remodelling complex atpase chain isw1. | 0.686 |
| Malapachy_0491 | FEN1 | A0A0M8MM31 | A0A0M9VQ18 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.551 |
| Malapachy_0491 | Malapachy_0638 | A0A0M8MM31 | A0A0M8MMR2 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Pin domain-like protein. | 0.551 |
| Malapachy_0491 | Malapachy_0762 | A0A0M8MM31 | A0A0M9VPK8 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Lymphoid-specific helicase-like protein. | 0.698 |
| Malapachy_0491 | Malapachy_1478 | A0A0M8MM31 | A0A0M9VNF1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Transcription elongation factor. | 0.547 |
| Malapachy_0491 | Malapachy_3005 | A0A0M8MM31 | A0A0M8MXW7 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Uncharacterized protein. | 0.538 |
| Malapachy_0491 | Malapachy_3342 | A0A0M8MM31 | A0A0M9VRF6 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Chromatin remodelling complex atpase chain isw1. | 0.698 |
| Malapachy_0638 | Malapachy_0491 | A0A0M8MMR2 | A0A0M8MM31 | Pin domain-like protein. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.551 |
| Malapachy_0638 | Malapachy_0762 | A0A0M8MMR2 | A0A0M9VPK8 | Pin domain-like protein. | Lymphoid-specific helicase-like protein. | 0.660 |