STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2980Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides. (395 aa)    
Predicted Functional Partners:
Malapachy_0099
Glycosyltransferase family 21 protein.
   
 
 0.936
Malapachy_1725
Lcb5-sphingolipid long chain base kinase.
    
 0.918
Malapachy_3287
Endo/exonuclease/phosphatase domain-containing protein.
     
 0.918
Malapachy_0056
Longevity assurance protein lag1 lac1.
    
 0.914
Malapachy_0945
Longevity-assurance protein.
    
 0.914
Malapachy_4200
Ypc1-alkaline ceramidase.
   
 
 0.909
Malapachy_0290
Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
 
    
 0.902
Malapachy_2790
Sphingosine hydroxylase; Belongs to the sterol desaturase family.
   
 
 0.886
Malapachy_2506
Putative acid sphingomyelinase.
     
 0.880
Malapachy_2505
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family.
     
 0.880
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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