node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Malapachy_0524 | Malapachy_0534 | A0A0M8MM17 | A0A0M9VN10 | Dihydrolipoamide succinyltransferase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.987 |
Malapachy_0524 | Malapachy_1545 | A0A0M8MM17 | A0A0M8MIL2 | Dihydrolipoamide succinyltransferase. | 2-oxoglutarate dehydrogenase complex e1 component mitochondrial. | 0.999 |
Malapachy_0524 | Malapachy_1597 | A0A0M8MM17 | A0A0M9VN92 | Dihydrolipoamide succinyltransferase. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.942 |
Malapachy_0524 | Malapachy_2752 | A0A0M8MM17 | A0A0M8MRR0 | Dihydrolipoamide succinyltransferase. | ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | 0.861 |
Malapachy_0524 | Malapachy_2966 | A0A0M8MM17 | A0A0M8MYX0 | Dihydrolipoamide succinyltransferase. | Pyruvate dehydrogenase x component. | 0.918 |
Malapachy_0524 | Malapachy_3011 | A0A0M8MM17 | A0A0M8MZ18 | Dihydrolipoamide succinyltransferase. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.989 |
Malapachy_0524 | Malapachy_3197 | A0A0M8MM17 | A0A0M8MY41 | Dihydrolipoamide succinyltransferase. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.986 |
Malapachy_0524 | Malapachy_3444 | A0A0M8MM17 | A0A0M8MXX3 | Dihydrolipoamide succinyltransferase. | Dihydrolipoyl dehydrogenase. | 0.999 |
Malapachy_0524 | Malapachy_3607 | A0A0M8MM17 | A0A0N0RSQ4 | Dihydrolipoamide succinyltransferase. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.832 |
Malapachy_0524 | Malapachy_3891 | A0A0M8MM17 | A0A0M8MK18 | Dihydrolipoamide succinyltransferase. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.943 |
Malapachy_0534 | Malapachy_0524 | A0A0M9VN10 | A0A0M8MM17 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoamide succinyltransferase. | 0.987 |
Malapachy_0534 | Malapachy_1545 | A0A0M9VN10 | A0A0M8MIL2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 2-oxoglutarate dehydrogenase complex e1 component mitochondrial. | 0.969 |
Malapachy_0534 | Malapachy_1597 | A0A0M9VN10 | A0A0M9VN92 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.720 |
Malapachy_0534 | Malapachy_2966 | A0A0M9VN10 | A0A0M8MYX0 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Pyruvate dehydrogenase x component. | 0.903 |
Malapachy_0534 | Malapachy_3011 | A0A0M9VN10 | A0A0M8MZ18 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.999 |
Malapachy_0534 | Malapachy_3197 | A0A0M9VN10 | A0A0M8MY41 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.876 |
Malapachy_0534 | Malapachy_3444 | A0A0M9VN10 | A0A0M8MXX3 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Dihydrolipoyl dehydrogenase. | 0.967 |
Malapachy_0534 | Malapachy_3607 | A0A0M9VN10 | A0A0N0RSQ4 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.586 |
Malapachy_0534 | Malapachy_3891 | A0A0M9VN10 | A0A0M8MK18 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.971 |
Malapachy_1545 | Malapachy_0524 | A0A0M8MIL2 | A0A0M8MM17 | 2-oxoglutarate dehydrogenase complex e1 component mitochondrial. | Dihydrolipoamide succinyltransferase. | 0.999 |