STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_3841Adenine phosphoribosyltransferase. (186 aa)    
Predicted Functional Partners:
Malapachy_2753
Gmp synthase.
  
 0.991
Malapachy_1143
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
 
 
 0.988
Malapachy_2952
Adenosine kinase.
   
 0.985
Malapachy_1970
Amp deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
 0.982
Malapachy_1183
Guanylate kinase.
  
 
 0.971
Malapachy_4086
Bifunctional purine biosynthesis protein ade10.
  
 0.971
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
  
 
 0.961
Malapachy_2899
Metallo-dependent phosphatase; Belongs to the 5'-nucleotidase family.
    
 0.948
Malapachy_3894
Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
   
 
  0.935
ADK2
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
  
 
 0.918
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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