STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_4271Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (280 aa)    
Predicted Functional Partners:
Malapachy_3256
Thymidylate synthase.
 
 0.996
Malapachy_1995
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.929
Malapachy_2120
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
     
 0.924
Malapachy_1144
Fthfs-domain-containing protein.
  
 
 0.921
Malapachy_1818
Methionyl-trna formyltransferase.
  
 
 0.914
Malapachy_1595
Phosphoribosylglycinamide formyltransferase.
   
 
 0.910
Malapachy_4086
Bifunctional purine biosynthesis protein ade10.
    
 0.904
Malapachy_0092
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
     
 0.895
Malapachy_3265
Folylpolyglutamate synthase.
     
 0.809
Malapachy_3205
Thymidylate kinase.
    
 0.747
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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