STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_0797Histone H2A; Belongs to the histone H2A family. (136 aa)    
Predicted Functional Partners:
Malapachy_1925
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.999
Malapachy_0811
Histone h2b; Belongs to the histone H2B family.
 
 0.999
Malapachy_3722
Ankyrin repeat protein.
    
 0.994
Malapachy_0685
Uncharacterized protein.
    
 0.981
Malapachy_2007
Ubiquitin domain containing protein.
   
 0.981
Malapachy_3593
Fact complex subunit spt16.
   
 
 0.980
Malapachy_1344
Histone H2A; Belongs to the histone H2A family.
  
0.978
Malapachy_3344
Set domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
    
 0.963
Malapachy_3342
Chromatin remodelling complex atpase chain isw1.
   
 0.955
Malapachy_3887
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.953
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.