STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_0834Molybdenum cofactor biosynthetic protein. (321 aa)    
Predicted Functional Partners:
Malapachy_2911
Cysteine desulfurase.
   
 0.990
URM1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]
    
 0.942
Malapachy_0291
Uncharacterized protein.
   
 0.879
Malapachy_2579
Small ubiquitin-related modifier.
   
 0.879
Malapachy_2999
Uncharacterized protein.
    
 0.871
Malapachy_4266
Autophagy-related protein 3.
    
 0.841
Malapachy_3642
Autophagy-related protein.
   
 0.833
Malapachy_0285
E2 ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.816
Malapachy_0685
Uncharacterized protein.
   
 0.808
Malapachy_1747
Nedd8-ubiquitin-like protein.
    
 0.779
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.