STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2682Acetyl-coenzyme a acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)    
Predicted Functional Partners:
Malapachy_1103
3-hydroxyacyl-dehydrogenase.
 
 0.996
Malapachy_1174
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.993
Malapachy_0529
Acyl-dehydrogenase.
  
 0.984
Malapachy_0662
Enoyl-hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.974
Malapachy_2780
Acetyl-c-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
0.955
Malapachy_2636
Acyl-oxidase.
  
 0.950
Malapachy_1930
Pot1-acetyl-c-peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.
  
0.945
Malapachy_0725
Acetyl-coenzyme A synthetase.
  
 
 0.936
Malapachy_0772
Citrate synthase; Belongs to the citrate synthase family.
  
 0.932
Malapachy_3011
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.930
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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