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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_2924General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (513 aa)    
Predicted Functional Partners:
Malapachy_0739
Dna repair helicase.
    
 0.999
Malapachy_0804
Transcription factor tfb4.
   
 0.999
Malapachy_1287
Dna repair helicase rad25.
    
 0.999
Malapachy_1256
Tfb1-subunit of rna polymerase ii transcription initiation factor tfiih.
    
 0.999
Malapachy_4095
Cdk-activating kinase assembly factor.
   
 0.998
Malapachy_2197
Transcription initiation factor iie subunit beta.
   
 0.994
Malapachy_2088
Tfa1-tfiie subunit (Transcription initiation factor) 66 kd.
   
 0.994
Malapachy_1182
Cmgc cdk cdk7 protein kinase; Belongs to the protein kinase superfamily.
   
 0.980
Malapachy_2371
Cyclin-like protein; Belongs to the cyclin family.
   
 0.971
Malapachy_0962
Transcription initiation factor iib.
    
 0.969
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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