Malapachy_3140 protein (Malassezia pachydermatis)

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Malapachy_3140

Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (310 aa)

Predicted Functional Partners:

Malapachy_0924

0.993

Malapachy_3759

0.978

Malapachy_2692

0.938

Malapachy_2914

0.826

Malapachy_1888

0.808

Malapachy_1924

0.687

Malapachy_2676

0.687

Malapachy_3278

0.653

Malapachy_2006

0.591

Malapachy_2005

0.591

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Malapachy_0924	Malapachy_1888	A0A0M9VQ03	A0A0M8MNW5	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Short-chain dehydrogenase reductase sdr.	0.896
Malapachy_0924	Malapachy_2005	A0A0M9VQ03	A0A0M8MU68	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Elongation of fatty acids protein.	0.691
Malapachy_0924	Malapachy_2006	A0A0M9VQ03	A0A0M8MTU5	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Elongation of fatty acids protein.	0.691
Malapachy_0924	Malapachy_2692	A0A0M9VQ03	A0A0M9VQV5	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Delta-12 fatty acid desaturase.	0.933
Malapachy_0924	Malapachy_2914	A0A0M9VQ03	A0A0M8MNI8	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.864
Malapachy_0924	Malapachy_3140	A0A0M9VQ03	A0A0M9VR56	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.993
Malapachy_0924	Malapachy_3759	A0A0M9VQ03	A0A0M9VPE2	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.989
Malapachy_1888	Malapachy_0924	A0A0M8MNW5	A0A0M9VQ03	Short-chain dehydrogenase reductase sdr.	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	0.896
Malapachy_1888	Malapachy_2005	A0A0M8MNW5	A0A0M8MU68	Short-chain dehydrogenase reductase sdr.	Elongation of fatty acids protein.	0.451
Malapachy_1888	Malapachy_2006	A0A0M8MNW5	A0A0M8MTU5	Short-chain dehydrogenase reductase sdr.	Elongation of fatty acids protein.	0.451
Malapachy_1888	Malapachy_2914	A0A0M8MNW5	A0A0M8MNI8	Short-chain dehydrogenase reductase sdr.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.855
Malapachy_1888	Malapachy_3140	A0A0M8MNW5	A0A0M9VR56	Short-chain dehydrogenase reductase sdr.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.808
Malapachy_1924	Malapachy_3140	A0A0M8MTT4	A0A0M9VR56	Negative regulator sulfur controller-3; Belongs to the SKP1 family.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.687
Malapachy_2005	Malapachy_0924	A0A0M8MU68	A0A0M9VQ03	Elongation of fatty acids protein.	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	0.691
Malapachy_2005	Malapachy_1888	A0A0M8MU68	A0A0M8MNW5	Elongation of fatty acids protein.	Short-chain dehydrogenase reductase sdr.	0.451
Malapachy_2005	Malapachy_2692	A0A0M8MU68	A0A0M9VQV5	Elongation of fatty acids protein.	Delta-12 fatty acid desaturase.	0.471
Malapachy_2005	Malapachy_2914	A0A0M8MU68	A0A0M8MNI8	Elongation of fatty acids protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.883
Malapachy_2005	Malapachy_3140	A0A0M8MU68	A0A0M9VR56	Elongation of fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.591
Malapachy_2005	Malapachy_3759	A0A0M8MU68	A0A0M9VPE2	Elongation of fatty acids protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.623
Malapachy_2006	Malapachy_0924	A0A0M8MTU5	A0A0M9VQ03	Elongation of fatty acids protein.	Tsc13-enoyl reductase involved in very long chain fatty acid elongation.	0.691

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