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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_3024Actin-like protein; Belongs to the actin family. (378 aa)    
Predicted Functional Partners:
Malapachy_3978
Act1-actin; Belongs to the actin family.
  
 
0.995
Malapachy_1148
Nonmuscle myosin heavy chain b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.995
Malapachy_2207
Actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 0.986
Malapachy_1696
Dynactin subunit 2.
   
 0.983
Malapachy_3596
Sac6-actin filament bundling fimbrin.
   
 
 0.976
Malapachy_4064
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.975
Malapachy_1291
Actin binding protein; Belongs to the actin family.
   
0.973
Malapachy_1048
Neural wiskott-aldrich syndrome protein.
    
 0.973
Malapachy_3448
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
 
0.971
Malapachy_1940
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.970
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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