| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DRE2 | Malapachy_0060 | A0A0N0RSD6 | A0A0M8MSC4 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.706 |
| DRE2 | Malapachy_1841 | A0A0N0RSD6 | A0A0M9VNY2 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.658 |
| DRE2 | Malapachy_1912 | A0A0N0RSD6 | A0A0M9VNT0 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Glutaredoxin. | 0.939 |
| DRE2 | Malapachy_3300 | A0A0N0RSD6 | A0A0M8MSQ6 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.879 |
| DRE2 | Malapachy_3770 | A0A0N0RSD6 | A0A0N0RS93 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.787 |
| DRE2 | Malapachy_4070 | A0A0N0RSD6 | A0A0M8MLZ2 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.449 |
| MET3 | Malapachy_3770 | A0A0M8MXD1 | A0A0N0RS93 | Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.561 |
| Malapachy_0060 | DRE2 | A0A0M8MSC4 | A0A0N0RSD6 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.706 |
| Malapachy_0060 | Malapachy_1358 | A0A0M8MSC4 | A0A0M8MLV4 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Hira-interacting protein 5. | 0.454 |
| Malapachy_0060 | Malapachy_1841 | A0A0M8MSC4 | A0A0M9VNY2 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.490 |
| Malapachy_0060 | Malapachy_1912 | A0A0M8MSC4 | A0A0M9VNT0 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Glutaredoxin. | 0.956 |
| Malapachy_0060 | Malapachy_3300 | A0A0M8MSC4 | A0A0M8MSQ6 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.817 |
| Malapachy_0060 | Malapachy_3770 | A0A0M8MSC4 | A0A0N0RS93 | Uncharacterized protein; Belongs to the BolA/IbaG family. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.880 |
| Malapachy_0204 | Malapachy_3770 | A0A0M9VNN6 | A0A0N0RS93 | Tim9-translocase of the mitochondrial inner membrane. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.493 |
| Malapachy_1234 | Malapachy_1358 | A0A0M8MQ38 | A0A0M8MLV4 | Iron-sulfur cluster assembly accessory protein isa2. | Hira-interacting protein 5. | 0.819 |
| Malapachy_1234 | Malapachy_1841 | A0A0M8MQ38 | A0A0M9VNY2 | Iron-sulfur cluster assembly accessory protein isa2. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.453 |
| Malapachy_1234 | Malapachy_1912 | A0A0M8MQ38 | A0A0M9VNT0 | Iron-sulfur cluster assembly accessory protein isa2. | Glutaredoxin. | 0.753 |
| Malapachy_1234 | Malapachy_3300 | A0A0M8MQ38 | A0A0M8MSQ6 | Iron-sulfur cluster assembly accessory protein isa2. | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.807 |
| Malapachy_1234 | Malapachy_3770 | A0A0M8MQ38 | A0A0N0RS93 | Iron-sulfur cluster assembly accessory protein isa2. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.483 |
| Malapachy_1234 | Malapachy_4070 | A0A0M8MQ38 | A0A0M8MLZ2 | Iron-sulfur cluster assembly accessory protein isa2. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.430 |