PAN3 protein (Malassezia pachydermatis) - STRING interaction network

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PAN3

PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (631 aa)

Predicted Functional Partners:

Malapachy_1950

0.999

Malapachy_1357

0.966

Malapachy_1847

0.878

Malapachy_0361

0.878

Malapachy_4184

0.878

Malapachy_2244

0.661

Malapachy_1405

0.635

Malapachy_0501

0.635

Malapachy_1704

0.625

Malapachy_4072

0.619

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Malapachy_0361	Malapachy_0501	A0A0M9VMV6	A0A0M8MM38	Rexo1 protein.	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	0.477
Malapachy_0361	Malapachy_1357	A0A0M9VMV6	A0A0M8MRA3	Rexo1 protein.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.778
Malapachy_0361	Malapachy_1405	A0A0M9VMV6	A0A0M8MJV5	Rexo1 protein.	Eukaryotic translation initiation factor 4e class i; Belongs to the eukaryotic initiation factor 4E family.	0.477
Malapachy_0361	Malapachy_1704	A0A0M9VMV6	A0A0M8MJI1	Rexo1 protein.	Dead-domain-containing protein; Belongs to the DEAD box helicase family.	0.499
Malapachy_0361	Malapachy_4072	A0A0M9VMV6	A0A0M8MUW7	Rexo1 protein.	Uncharacterized protein.	0.477
Malapachy_0361	PAN3	A0A0M9VMV6	A0A0N0RSP5	Rexo1 protein.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	0.878
Malapachy_0501	Malapachy_0361	A0A0M8MM38	A0A0M9VMV6	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Rexo1 protein.	0.477
Malapachy_0501	Malapachy_1357	A0A0M8MM38	A0A0M8MRA3	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.903
Malapachy_0501	Malapachy_1405	A0A0M8MM38	A0A0M8MJV5	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Eukaryotic translation initiation factor 4e class i; Belongs to the eukaryotic initiation factor 4E family.	0.887
Malapachy_0501	Malapachy_1704	A0A0M8MM38	A0A0M8MJI1	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Dead-domain-containing protein; Belongs to the DEAD box helicase family.	0.774
Malapachy_0501	Malapachy_1847	A0A0M8MM38	A0A0M8ML98	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Nuclear cut8 family protein.	0.477
Malapachy_0501	Malapachy_1950	A0A0M8MM38	A0A0M8MT30	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Pab-dependent poly-specific ribonuclease subunit pan2.	0.575
Malapachy_0501	Malapachy_4184	A0A0M8MM38	A0A0M9VP58	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	Rna exonuclease 4.	0.483
Malapachy_0501	PAN3	A0A0M8MM38	A0A0N0RSP5	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	0.635
Malapachy_1357	Malapachy_0361	A0A0M8MRA3	A0A0M9VMV6	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Rexo1 protein.	0.778
Malapachy_1357	Malapachy_0501	A0A0M8MRA3	A0A0M8MM38	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Eukaryotic translation initiation factor 4e class ii; Belongs to the eukaryotic initiation factor 4E family.	0.903
Malapachy_1357	Malapachy_1405	A0A0M8MRA3	A0A0M8MJV5	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Eukaryotic translation initiation factor 4e class i; Belongs to the eukaryotic initiation factor 4E family.	0.915
Malapachy_1357	Malapachy_1704	A0A0M8MRA3	A0A0M8MJI1	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Dead-domain-containing protein; Belongs to the DEAD box helicase family.	0.849
Malapachy_1357	Malapachy_1847	A0A0M8MRA3	A0A0M8ML98	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Nuclear cut8 family protein.	0.778
Malapachy_1357	Malapachy_1950	A0A0M8MRA3	A0A0M8MT30	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Pab-dependent poly-specific ribonuclease subunit pan2.	0.965

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