STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Malapachy_3602Isopentenyl-diphosphate delta-isomerase. (248 aa)    
Predicted Functional Partners:
Malapachy_2418
Diphosphomevalonate decarboxylase.
  
 
 0.984
Malapachy_4067
Isoprenoid biosynthesis-related protein.
 
 
 0.973
Malapachy_4177
Geranylgeranyl diphosphate type iii; Belongs to the FPP/GGPP synthase family.
  
 
 0.965
Malapachy_2533
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.912
Malapachy_0530
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
  
 
 0.888
Malapachy_4218
Farnesyl-diphosphate farnesyltransferase.
 
 
 0.872
Malapachy_1174
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
  
 0.851
Malapachy_0981
Squalene monooxygenase.
   
  
 0.833
Malapachy_1475
Coq1-hexaprenyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.779
Malapachy_0043
3-hydroxy-3-methylglutaryl coenzyme A reductase.
 
  
 0.778
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.