A0A1S7UKA1 protein (Rosellinia necatrix) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

A0A1S7UKA1

Putative glutamine amidotransferase subunit pdxT. (217 aa)

Predicted Functional Partners:

A0A1W2TDQ2

0.785

A0A1W2TS64

0.683

A0A1W2TV01

0.605

A0A1S7UKF0

0.587

A0A1W2TGU5

0.587

A0A1W2TQZ0

0.564

A0A1W2TB54

0.550

A0A1W2THM9

0.539

A0A1W2THK9

0.528

A0A1S7UMM0

0.510

Your Current Organism:

Rosellinia necatrix

NCBI taxonomy Id: 77044
Other names: R. necatrix

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1S7UKA1	A0A1S7UKF0	Putative glutamine amidotransferase subunit pdxT.	Putative RNA polymerase Rpb3 insert domain-containing protein.	0.587
A0A1S7UKA1	A0A1S7UMM0	Putative glutamine amidotransferase subunit pdxT.	Putative lysyl-tRNA synthetase.	0.510
A0A1S7UKA1	A0A1W2TB54	Putative glutamine amidotransferase subunit pdxT.	Putative glutathione S-transferase-like protein; Belongs to the GST superfamily.	0.550
A0A1S7UKA1	A0A1W2TDQ2	Putative glutamine amidotransferase subunit pdxT.	Putative elongation factor 1-beta; Belongs to the EF-1-beta/EF-1-delta family.	0.785
A0A1S7UKA1	A0A1W2TGU5	Putative glutamine amidotransferase subunit pdxT.	Putative DNA-directed RNA polymerases i and iii 40 kDa polypeptide.	0.587
A0A1S7UKA1	A0A1W2THK9	Putative glutamine amidotransferase subunit pdxT.	Putative methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.528
A0A1S7UKA1	A0A1W2THM9	Putative glutamine amidotransferase subunit pdxT.	Putative elongation factor 1-gamma protein; Belongs to the GST superfamily.	0.539
A0A1S7UKA1	A0A1W2TQZ0	Putative glutamine amidotransferase subunit pdxT.	Putative methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.564
A0A1S7UKA1	A0A1W2TS64	Putative glutamine amidotransferase subunit pdxT.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.683
A0A1S7UKA1	A0A1W2TV01	Putative glutamine amidotransferase subunit pdxT.	Putative prion formation protein 1.	0.605
A0A1S7UKF0	A0A1S7UKA1	Putative RNA polymerase Rpb3 insert domain-containing protein.	Putative glutamine amidotransferase subunit pdxT.	0.587
A0A1S7UKF0	A0A1S7UMM0	Putative RNA polymerase Rpb3 insert domain-containing protein.	Putative lysyl-tRNA synthetase.	0.492
A0A1S7UKF0	A0A1W2TB54	Putative RNA polymerase Rpb3 insert domain-containing protein.	Putative glutathione S-transferase-like protein; Belongs to the GST superfamily.	0.665
A0A1S7UKF0	A0A1W2TGU5	Putative RNA polymerase Rpb3 insert domain-containing protein.	Putative DNA-directed RNA polymerases i and iii 40 kDa polypeptide.	0.807
A0A1S7UKF0	A0A1W2THM9	Putative RNA polymerase Rpb3 insert domain-containing protein.	Putative elongation factor 1-gamma protein; Belongs to the GST superfamily.	0.665
A0A1S7UKF0	A0A1W2TV01	Putative RNA polymerase Rpb3 insert domain-containing protein.	Putative prion formation protein 1.	0.504
A0A1S7UMM0	A0A1S7UKA1	Putative lysyl-tRNA synthetase.	Putative glutamine amidotransferase subunit pdxT.	0.510
A0A1S7UMM0	A0A1S7UKF0	Putative lysyl-tRNA synthetase.	Putative RNA polymerase Rpb3 insert domain-containing protein.	0.492
A0A1S7UMM0	A0A1W2TB54	Putative lysyl-tRNA synthetase.	Putative glutathione S-transferase-like protein; Belongs to the GST superfamily.	0.710
A0A1S7UMM0	A0A1W2TGU5	Putative lysyl-tRNA synthetase.	Putative DNA-directed RNA polymerases i and iii 40 kDa polypeptide.	0.492

page 1 of 5

Network Stats

number of nodes:

5

number of edges:

5

average node degree:

2

avg. local clustering coefficient:

0.833

expected number of edges:

4

PPI enrichment p-value:

0.375

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:2000169

Regulation of peptidyl-cysteine S-nitrosylation

2 of 4

3.16

1.37

0.0125

GO:0098974

Postsynaptic actin cytoskeleton organization

2 of 7

2.92

1.31

0.0150

GO:0042730

Fibrinolysis

2 of 9

2.81

1.31

0.0150

GO:0060307

Regulation of ventricular cardiac muscle cell membrane repolarization

2 of 11

2.73

1.3

0.0150

GO:1901385

Regulation of voltage-gated calcium channel activity

2 of 21

2.44

1.12

0.0264

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050998

Nitric-oxide synthase binding

2 of 9

2.81

1.34

0.0134

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0002102

Podosome

2 of 13

2.65

1.35

0.0127

GO:0033017

Sarcoplasmic reticulum membrane

2 of 18

2.51

1.34

0.0127

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:32351978

(2020) Erysipelothrix Spp.: Past, Present, and Future Directions in Vaccine Research.

2 of 3

3.29

2.04

0.0015

PMID:38254464

(2024) Pathogenic Potential of Coagulase-Positive Staphylococcus Strains Isolated from Aviary Capercaillies and Free-Living Birds in Southeastern Poland.

2 of 4

3.16

2.03

0.0015

PMID:31078554

(2019) How Environmental Fungi Cause a Range of Clinical Outcomes in Susceptible Hosts.

2 of 9

2.81

1.83

0.0027

PMID:22229971

(2012) Biology and pathogenesis of Acanthamoeba.

2 of 10

2.77

1.83

0.0027

PMID:37889324

(2023) Gallibacterium anatis infection in poultry: a comprehensive review.

2 of 13

2.65

1.77

0.0031

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:26252

Mixed, incl. Regulation of peptidyl-cysteine S-nitrosylation, and PKHG1/2/3, pleckstrin homology (PH) domain

3 of 6

3.16

3.77

5.32e-06

CL:19214

Mixed, incl. Fibrinolysis, and Fibrinogen

2 of 12

2.69

1.65

0.0047

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-8964041

LDL remodeling

2 of 9

2.81

1.48

0.0085

MAP-8963899

Plasma lipoprotein remodeling

2 of 29

2.3

1.01

0.0360

Tissue Expression (TISSUES)

tissue

description

count in network

strength

signal

false discovery rate

BTO:0000562

Heart

2 of 217

1.43

0.94

0.0195

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005577

Fibrinogen complex

2 of 8

2.86

1.58

0.0062

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0797

Tissue remodeling

2 of 2

3.47

2.7

0.00018

KW-0280

Fibrinolysis

2 of 2

3.47

2.7

0.00018

KW-0420

Kringle

2 of 14

2.62

2.21

0.00071

KW-0720

Serine protease

2 of 43

2.13

1.55

0.0049

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR023317

Peptidase S1A, plasmin

2 of 2

3.47

1.8

0.0033

IPR003609

PAN/Apple domain

2 of 4

3.16

1.72

0.0041

IPR038178

Kringle superfamily

2 of 14

2.62

1.23

0.0190

IPR018056

Kringle, conserved site

2 of 13

2.65

1.23

0.0190

IPR000001

Kringle

2 of 14

2.62

1.23

0.0190

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00130

Kringle domain

2 of 14

2.62

1.49

0.0079

SM00462

Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain

2 of 26

2.35

1.33

0.0123

SM00020

Trypsin-like serine protease

2 of 63

1.97

0.91

0.0451

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