STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1W2THB91-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (259 aa)    
Predicted Functional Partners:
A0A1W2TBW9
Histidine biosynthesis trifunctional protein.
  
 
 0.994
A0A1W2TMK5
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
  
 
 0.972
A0A1W2TDV2
Putative ATP phosphoribosyltransferase.
  
 
 0.957
A0A1S7ULC4
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.956
A0A1W2TNS9
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
 
 0.941
A0A1S8AAF1
Putative histidinol-phosphate aminotransferase.
  
  
 0.879
A0A1W2TW21
Tryptophan synthase.
  
 
 0.871
A0A1S7UMF7
Putative SNF2-like protein.
  
 
 0.836
A0A1W2THK7
Putative adenosinetriphosphatase.
  
 
 0.836
A0A1W2TMC3
Putative C-5 cytosine-specific DNA.
  
 
 0.836
Your Current Organism:
Rosellinia necatrix
NCBI taxonomy Id: 77044
Other names: R. necatrix
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.