STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1W2THQ5Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1273 aa)    
Predicted Functional Partners:
A0A1S7UHU6
Putative SPRY domain-containing protein.
    
 0.998
A0A1W2TBP4
Putative Set1 complex component swd1.
    
 0.998
A0A1W2TD81
Putative WD repeat-containing protein.
    
 0.988
A0A1W2TDH6
Putative dpy-30 domain-containing protein.
    
 0.981
A0A1W2TI37
Putative wd repeat containing protein 82 protein.
    
 0.980
A0A1S7UJW7
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.978
A0A1W2TEN7
Putative histone H3-like centromeric protein cse-4.
    
 0.975
A0A1W2TUB2
Histone H3; Belongs to the histone H3 family.
    
 0.975
A0A1W2TN68
Histone H2A; Belongs to the histone H2A family.
    
 0.953
A0A1W2TH51
Putative histone-lysine N-H3 lysine-36 specific; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
   
0.951
Your Current Organism:
Rosellinia necatrix
NCBI taxonomy Id: 77044
Other names: R. necatrix
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.