STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA07476.1D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (372 aa)    
Predicted Functional Partners:
tpiA_2
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.983
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.966
maeB
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
   
 0.959
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
   
 0.950
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.948
gap
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.937
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.935
nifJ
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.935
ppdK
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.921
fba
Fructose-bisphosphate aldolase, class II.
  
 
 0.917
Your Current Organism:
Prevotella bryantii
NCBI taxonomy Id: 77095
Other names: Bacteroides (Prevotella) ruminicola subsp. brevis biovar 3, CIP 105474, DSM 11371, P. bryantii, strain B14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.