node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEN02068.1 | SEO01550.1 | SAMN04490369_10014 | SAMN04490369_103818 | Hypothetical protein. | Putative hydrolase of the HAD superfamily. | 0.929 |
SEN02068.1 | cpdA | SAMN04490369_10014 | SAMN04490369_100718 | Hypothetical protein. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.916 |
SEN02068.1 | surE | SAMN04490369_10014 | SAMN04490369_102424 | Hypothetical protein. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.920 |
SEO01550.1 | SEN02068.1 | SAMN04490369_103818 | SAMN04490369_10014 | Putative hydrolase of the HAD superfamily. | Hypothetical protein. | 0.929 |
SEO01550.1 | SEO01576.1 | SAMN04490369_103818 | SAMN04490369_103819 | Putative hydrolase of the HAD superfamily. | Heat shock protein Hsp15; Belongs to the HSP15 family. | 0.923 |
SEO01550.1 | cpdA | SAMN04490369_103818 | SAMN04490369_100718 | Putative hydrolase of the HAD superfamily. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.926 |
SEO01550.1 | guaA | SAMN04490369_103818 | SAMN04490369_102728 | Putative hydrolase of the HAD superfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.922 |
SEO01550.1 | guaB | SAMN04490369_103818 | SAMN04490369_102729 | Putative hydrolase of the HAD superfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.931 |
SEO01550.1 | nadD | SAMN04490369_103818 | SAMN04490369_100674 | Putative hydrolase of the HAD superfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.918 |
SEO01550.1 | pncB | SAMN04490369_103818 | SAMN04490369_103433 | Putative hydrolase of the HAD superfamily. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.918 |
SEO01550.1 | purA | SAMN04490369_103818 | SAMN04490369_100772 | Putative hydrolase of the HAD superfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.921 |
SEO01550.1 | surE | SAMN04490369_103818 | SAMN04490369_102424 | Putative hydrolase of the HAD superfamily. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.924 |
SEO01550.1 | upp | SAMN04490369_103818 | SAMN04490369_102011 | Putative hydrolase of the HAD superfamily. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.917 |
SEO01576.1 | SEO01550.1 | SAMN04490369_103819 | SAMN04490369_103818 | Heat shock protein Hsp15; Belongs to the HSP15 family. | Putative hydrolase of the HAD superfamily. | 0.923 |
cpdA | SEN02068.1 | SAMN04490369_100718 | SAMN04490369_10014 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Hypothetical protein. | 0.916 |
cpdA | SEO01550.1 | SAMN04490369_100718 | SAMN04490369_103818 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Putative hydrolase of the HAD superfamily. | 0.926 |
cpdA | guaA | SAMN04490369_100718 | SAMN04490369_102728 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.699 |
cpdA | guaB | SAMN04490369_100718 | SAMN04490369_102729 | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.414 |
guaA | SEO01550.1 | SAMN04490369_102728 | SAMN04490369_103818 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Putative hydrolase of the HAD superfamily. | 0.922 |
guaA | cpdA | SAMN04490369_102728 | SAMN04490369_100718 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.699 |