STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACL1ATP-citrate synthase subunit 1; Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols; Belongs to the succinate/malate CoA ligase alpha subunit family. (674 aa)    
Predicted Functional Partners:
acl2
ATP citrate lyase subunit 2.
 
 
 0.999
SMAC_02401
Citrate synthase; Belongs to the citrate synthase family.
  
 0.983
SMAC_05990
Citrate synthase; Belongs to the citrate synthase family.
  
 0.983
SMAC_09047
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.973
SMAC_07106
Malate dehydrogenase.
  
 0.963
SMAC_08400
Malate dehydrogenase.
  
 0.963
SMAC_03518
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.954
SMAC_05967
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.944
SMAC_09567
WGS project CABT00000000 data, contig 2.101.
   
 
 0.911
SMAC_00695
WGS project CABT00000000 data, contig 2.2.
     
 0.902
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.