Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
F6Q7P2_CIOINUncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (312 aa)    
Predicted Functional Partners:
F6VZQ1_CIOIN
FMN hydroxy acid dehydrogenase domain-containing protein.
   
 
 0.928
F6SZD3_CIOIN
FMN hydroxy acid dehydrogenase domain-containing protein.
   
 
 0.928
LOC100178763
Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.928
LOC100179329
Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
     
 0.710
F6RT01_CIOIN
Uncharacterized protein.
   
  
 0.666
LOC100178162
Pyridoxal kinase-like.
     
 0.664
F6SAH8_CIOIN
Uncharacterized protein.
  
  
 0.616
F7ANQ7_CIOIN
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
 
 0.603
H2Y2P2_CIOIN
Fibrinogen C-terminal domain-containing protein.
    
   0.586
F6SRD6_CIOIN
Alpha-tubulin N-acetyltransferase; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynam [...]
   
  
 0.577
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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