Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F6PHT0_CIOINUncharacterized protein. (405 aa)    
Predicted Functional Partners:
F6Z5I5_CIOIN
Ephrin_rec_like domain-containing protein.
 
  
  0.897
F6Z4F9_CIOIN
Uncharacterized protein.
 
  
  0.593
su(h)
Suppressor of hairless homolog; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional expression of Brachyury, suggesting that it participates in notochord differentiation.
    
 0.560
F7B5L6_CIOIN
Uncharacterized protein.
    
 0.560
LOC100175930
Uncharacterized protein.
  
 
  0.532
H2XVU8_CIOIN
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.508
delta
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.443
LOC100101826
Uncharacterized protein.
   
 0.439
H2XLQ1_CIOIN
Uncharacterized protein.
 
  
  0.432
H2XYL9_CIOIN
Uncharacterized protein.
  
     0.422
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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