Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100181739Uncharacterized protein. (259 aa)    
Predicted Functional Partners:
LOC494392
Uncharacterized protein LOC494392.
    
 0.510
LOC100178802
Transcription elongation factor SPT5.
   
 0.490
F6QR00_CIOIN
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.483
LOC100177778
DNA-directed RNA polymerase II subunit RPB7.
    
 0.460
F6XIG6_CIOIN
RPOL4c domain-containing protein.
    
 0.460
H2XJG6_CIOIN
Uncharacterized protein.
    
 0.460
LOC100181341
DNA-directed RNA polymerase II subunit RPB11-a isoform X1.
    
 0.460
LOC101242260
DNA-directed RNA polymerases I, II, and III subunit RPABC4.
    
 0.460
H2XVJ2_CIOIN
Uncharacterized protein.
    
 0.460
LOC100178283
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
 0.459
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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