Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Zf(c2h2)-114General transcription factor IIH subunit. (395 aa)    
Predicted Functional Partners:
LOC100183594
General transcription and DNA repair factor IIH helicase subunit XPB.
    
 0.999
F6RMT1_CIOIN
Uncharacterized protein.
    
 0.999
LOC100184165
General transcription factor IIH subunit 3-like.
   
 0.999
zf(ring)-55
Zinc finger protein.
   
 0.998
LOC100177816
cyclin-H; Belongs to the cyclin family.
   
 0.989
F7BHW5_CIOIN
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
   
 0.987
LOC100175005
HTH TFE/IIEalpha-type domain-containing protein.
   
 0.986
LOC100182343
Transcription initiation factor IIB-like.
    
 0.959
F6S7U3_CIOIN
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.957
F6S7T3_CIOIN
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.957
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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