STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100183355Uncharacterized protein. (496 aa)    
Predicted Functional Partners:
F6RMZ6_CIOIN
Uncharacterized protein.
    
   0.920
TRM5_CIOIN
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
   
  
 0.829
LOC100184413
TRUD domain-containing protein.
   
  
 0.826
LOC100181071
TRUD domain-containing protein.
   
  
 0.826
F6TLE4_CIOIN
PseudoU_synth_1 domain-containing protein.
   
  
 0.752
H2Y0C0_CIOIN
SAM_MT_TRM5_TYW2 domain-containing protein.
   
  
 0.748
F6WN37_CIOIN
Uncharacterized protein.
   
  
 0.703
LOC100179078
tRNA pseudouridine(38/39) synthase.
   
  
 0.701
F6U2M6_CIOIN
PUA domain-containing protein.
   
  
 0.697
LOC113473990
RRM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
      
 0.694
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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