Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IqgapRas-GAP domain-containing protein. (549 aa)    
Predicted Functional Partners:
cdc42
Uncharacterized protein.
   
 0.982
H2Y088_CIOIN
Calponin-homology (CH) domain-containing protein.
 
     0.947
H2XMN3_CIOIN
Uncharacterized protein.
   
 
 0.848
LOC100184096
Anillin-like isoform X1.
   
 0.824
F6RST4_CIOIN
F-BAR domain-containing protein.
   
 
 0.782
F7BGY7_CIOIN
Uncharacterized protein.
   
 0.767
Cibeta-catenin
Uncharacterized protein.
   
 0.718
F6TZA7_CIOIN
Uncharacterized protein.
   
 0.718
rhoc
RhoA protein.
   
 0.714
Raf1
Uncharacterized protein.
    
 0.704
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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