Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irf-like-3IRF tryptophan pentad repeat domain-containing protein. (530 aa)    
Predicted Functional Partners:
LOC778553
Uncharacterized protein.
    
 0.716
F7BIB7_CIOIN
Protein kinase domain-containing protein.
      
 0.630
ikk-epsilon
ikappaB kinase isoform X1.
    
 0.614
erf2
Transcription factor protein.
    
 
 0.568
LOC100177133
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.545
F6U7X2_CIOIN
PIPK domain-containing protein.
      
 0.513
F6T957_CIOIN
Uncharacterized protein.
    
  0.508
pias
Uncharacterized protein.
    
 0.501
F6Q8U3_CIOIN
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
      
 0.494
F6RE18_CIOIN
ATP synthase subunit gamma.
      
 0.492
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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