F6UPI8_CIOIN protein (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

F6UPI8_CIOIN

Fork-head domain-containing protein. (596 aa)

Predicted Functional Partners:

LOC100178575

0.764

smad2/3a

0.764

LOC100186645

0.747

smad4

0.586

F6SFW9_CIOIN

0.507

LOC100184902

0.501

Gataa

0.497

F6S4F7_CIOIN

0.472

LOC100179349

0.467

Smad1/5

0.467

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6S4F7_CIOIN	F6SFW9_CIOIN	ENSCINP00000016461	ENSCINP00000024412	Non-specific serine/threonine protein kinase.	Fork-head domain-containing protein.	0.632
F6S4F7_CIOIN	F6UPI8_CIOIN	ENSCINP00000016461	ENSCINP00000001615	Non-specific serine/threonine protein kinase.	Fork-head domain-containing protein.	0.472
F6S4F7_CIOIN	LOC100178575	ENSCINP00000016461	ENSCINP00000012794	Non-specific serine/threonine protein kinase.	Mothers against decapentaplegic homolog.	0.579
F6S4F7_CIOIN	LOC100179349	ENSCINP00000016461	ENSCINP00000002361	Non-specific serine/threonine protein kinase.	Integrator complex subunit 8-like.	0.445
F6S4F7_CIOIN	Smad1/5	ENSCINP00000016461	ENSCINP00000012287	Non-specific serine/threonine protein kinase.	MH2 domain-containing protein.	0.445
F6S4F7_CIOIN	smad2/3a	ENSCINP00000016461	ENSCINP00000036287	Non-specific serine/threonine protein kinase.	Mothers against decapentaplegic homolog.	0.579
F6S4F7_CIOIN	smad4	ENSCINP00000016461	ENSCINP00000011529	Non-specific serine/threonine protein kinase.	Mothers against decapentaplegic homolog.	0.912
F6SFW9_CIOIN	F6S4F7_CIOIN	ENSCINP00000024412	ENSCINP00000016461	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase.	0.632
F6SFW9_CIOIN	F6UPI8_CIOIN	ENSCINP00000024412	ENSCINP00000001615	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.507
F6SFW9_CIOIN	Gataa	ENSCINP00000024412	ENSCINP00000009159	Fork-head domain-containing protein.	Uncharacterized protein.	0.504
F6SFW9_CIOIN	LOC100178575	ENSCINP00000024412	ENSCINP00000012794	Fork-head domain-containing protein.	Mothers against decapentaplegic homolog.	0.502
F6SFW9_CIOIN	smad2/3a	ENSCINP00000024412	ENSCINP00000036287	Fork-head domain-containing protein.	Mothers against decapentaplegic homolog.	0.502
F6SFW9_CIOIN	smad4	ENSCINP00000024412	ENSCINP00000011529	Fork-head domain-containing protein.	Mothers against decapentaplegic homolog.	0.571
F6UPI8_CIOIN	F6S4F7_CIOIN	ENSCINP00000001615	ENSCINP00000016461	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase.	0.472
F6UPI8_CIOIN	F6SFW9_CIOIN	ENSCINP00000001615	ENSCINP00000024412	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.507
F6UPI8_CIOIN	Gataa	ENSCINP00000001615	ENSCINP00000009159	Fork-head domain-containing protein.	Uncharacterized protein.	0.497
F6UPI8_CIOIN	LOC100178575	ENSCINP00000001615	ENSCINP00000012794	Fork-head domain-containing protein.	Mothers against decapentaplegic homolog.	0.764
F6UPI8_CIOIN	LOC100179349	ENSCINP00000001615	ENSCINP00000002361	Fork-head domain-containing protein.	Integrator complex subunit 8-like.	0.467
F6UPI8_CIOIN	LOC100184902	ENSCINP00000001615	ENSCINP00000015197	Fork-head domain-containing protein.	Geminin.	0.501
F6UPI8_CIOIN	LOC100186645	ENSCINP00000001615	ENSCINP00000033825	Fork-head domain-containing protein.	Uncharacterized protein LOC100186645.	0.747