STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6QCF9_CIOINSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2069 aa)    
Predicted Functional Partners:
F6ZAK6_CIOIN
Uncharacterized protein.
   
 0.789
H2XKY9_CIOIN
Uncharacterized protein.
   
 0.789
H2XMW4_CIOIN
Uncharacterized protein.
   
 0.789
H2XR09_CIOIN
Uncharacterized protein.
   
 0.789
H2XXV0_CIOIN
Uncharacterized protein.
   
 0.789
H2XY46_CIOIN
Uncharacterized protein.
   
 0.789
F6VJS2_CIOIN
SH3 domain-containing protein.
   
 0.670
F6SKF5_CIOIN
Uncharacterized protein.
   
0.651
Cam
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
    
 
 0.650
F6REB5_CIOIN
VWFA domain-containing protein.
   
 0.611
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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