STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F7B4Q5_CIOINUncharacterized protein. (561 aa)    
Predicted Functional Partners:
F7ANR5_CIOIN
CPSF_A domain-containing protein.
    
 0.977
LOC100175879
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.912
LOC100182514
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.784
F7B3P4_CIOIN
Uncharacterized protein.
   
 0.757
LOC100179498
DNA repair protein complementing XP-A cells homolog.
    
 0.741
ckn1
Cockayne syndrome 1 homolog.
    
 0.738
LOC100182035
COP9 signalosome complex subunit 8-like.
    
 0.729
H2XUA5_CIOIN
Uncharacterized protein.
   
 0.729
LOC100183592
COP9 signalosome complex subunit 4.
    
 0.727
LOC113474404
COP9 signalosome complex subunit 7a-like.
    
 0.720
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.