MTAP_CIOIN protein (Ciona intestinalis) - STRING interaction network

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MTAP_CIOIN

S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (282 aa)

Predicted Functional Partners:

LOC100182449

0.983

LOC100176863

0.976

F6WYU2_CIOIN

0.973

LOC100186031

0.861

F6ZFG0_CIOIN

0.855

F6PJS6_CIOIN

0.855

LOC100181600

0.848

LOC100184518

0.844

F6SKP5_CIOIN

0.797

F6TT30_CIOIN

0.781

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PJS6_CIOIN	F6SKP5_CIOIN	ENSCINP00000028721	ENSCINP00000008305	AB hydrolase-1 domain-containing protein.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.864
F6PJS6_CIOIN	F6TT30_CIOIN	ENSCINP00000028721	ENSCINP00000024093	AB hydrolase-1 domain-containing protein.	CTP_transf_like domain-containing protein.	0.567
F6PJS6_CIOIN	F6ZFG0_CIOIN	ENSCINP00000028721	ENSCINP00000017686	AB hydrolase-1 domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.433
F6PJS6_CIOIN	MTAP_CIOIN	ENSCINP00000028721	ENSCINP00000005182	AB hydrolase-1 domain-containing protein.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.855
F6SKP5_CIOIN	F6PJS6_CIOIN	ENSCINP00000008305	ENSCINP00000028721	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	AB hydrolase-1 domain-containing protein.	0.864
F6SKP5_CIOIN	F6TT30_CIOIN	ENSCINP00000008305	ENSCINP00000024093	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	CTP_transf_like domain-containing protein.	0.971
F6SKP5_CIOIN	F6ZFG0_CIOIN	ENSCINP00000008305	ENSCINP00000017686	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	AB hydrolase-1 domain-containing protein.	0.864
F6SKP5_CIOIN	LOC100184518	ENSCINP00000008305	ENSCINP00000031490	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Uridine phosphorylase 2.	0.975
F6SKP5_CIOIN	LOC100186031	ENSCINP00000008305	ENSCINP00000035369	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	Adenine phosphoribosyltransferase-like.	0.956
F6SKP5_CIOIN	MTAP_CIOIN	ENSCINP00000008305	ENSCINP00000005182	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.797
F6TT30_CIOIN	F6PJS6_CIOIN	ENSCINP00000024093	ENSCINP00000028721	CTP_transf_like domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.567
F6TT30_CIOIN	F6SKP5_CIOIN	ENSCINP00000024093	ENSCINP00000008305	CTP_transf_like domain-containing protein.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.971
F6TT30_CIOIN	F6ZFG0_CIOIN	ENSCINP00000024093	ENSCINP00000017686	CTP_transf_like domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.567
F6TT30_CIOIN	MTAP_CIOIN	ENSCINP00000024093	ENSCINP00000005182	CTP_transf_like domain-containing protein.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.781
F6WYU2_CIOIN	LOC100176863	ENSCINP00000005777	ENSCINP00000019159	PABS domain-containing protein.	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.	0.955
F6WYU2_CIOIN	LOC100182449	ENSCINP00000005777	ENSCINP00000000274	PABS domain-containing protein.	Methylthioribose-1-phosphate isomerase-like; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.431
F6WYU2_CIOIN	MTAP_CIOIN	ENSCINP00000005777	ENSCINP00000005182	PABS domain-containing protein.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.973
F6ZFG0_CIOIN	F6PJS6_CIOIN	ENSCINP00000017686	ENSCINP00000028721	AB hydrolase-1 domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.433
F6ZFG0_CIOIN	F6SKP5_CIOIN	ENSCINP00000017686	ENSCINP00000008305	AB hydrolase-1 domain-containing protein.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.864
F6ZFG0_CIOIN	F6TT30_CIOIN	ENSCINP00000017686	ENSCINP00000024093	AB hydrolase-1 domain-containing protein.	CTP_transf_like domain-containing protein.	0.567

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