Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100176828Vesicular integral-membrane protein VIP36. (340 aa)    
Predicted Functional Partners:
H2XWC1_CIOIN
GOLD domain-containing protein.
   
 0.847
LOC100183335
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
    
 0.838
LOC100176668
Transmembrane emp24 domain-containing protein 2.
   
 0.827
LOC100183132
Uncharacterized protein.
   
  
 0.718
LOC100183161
Multivesicular body subunit 12B-like isoform X1.
      
 0.713
LOC100182407
Protein SEC13 homolog; Belongs to the WD repeat SEC13 family.
   
 
 0.708
F6RHH3_CIOIN
Uncharacterized protein.
    
 0.698
F6YIU2_CIOIN
WD_REPEATS_REGION domain-containing protein.
     
 0.698
F6XHQ2_CIOIN
Uncharacterized protein.
   
 
 0.696
LOC100181871
t-SNARE coiled-coil homology domain-containing protein.
     
 0.694
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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