STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6YGR5_CIOINSorting nexin; Involved in several stages of intracellular trafficking. (410 aa)    
Predicted Functional Partners:
H2XQC1_CIOIN
PX domain-containing protein.
   
0.972
LOC100181786
Sorting nexin-5.
     
 
0.900
LOC100184638
Sorting nexin-33-like.
     
 0.800
LOC100179839
Sorting nexin-4-like.
   
 0.740
F6VBD5_CIOIN
Uncharacterized protein.
     
 0.721
F6WRU8_CIOIN
Uncharacterized protein.
   
 0.709
F7AMF6_CIOIN
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.693
LOC100180632
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.690
LOC100176748
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.679
LOC100179535
Vacuolar protein sorting-associated protein 26B.
    
 
 0.678
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.