STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100176748Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (183 aa)    
Predicted Functional Partners:
LOC100180632
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.999
LOC100179535
Vacuolar protein sorting-associated protein 26B.
   
 0.999
H2XQC1_CIOIN
PX domain-containing protein.
   
 0.982
F6T0L9_CIOIN
Rab-GAP TBC domain-containing protein.
    
 
 0.942
LOC100180887
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.902
LOC100176145
Sorting nexin-12-like isoform X1.
   
 0.896
H2XM49_CIOIN
PX domain-containing protein.
   
 0.896
LOC100186572
Down syndrome critical region protein 3 homolog.
   
 
 0.813
F7AFD2_CIOIN
Uncharacterized protein.
    
 
 0.801
H2Y2U9_CIOIN
Uncharacterized protein.
    
 
 0.799
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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