STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6TZ29_CIOINUbiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (678 aa)    
Predicted Functional Partners:
LOC100186367
Gamma-aminobutyric acid receptor-associated protein.
   
 0.999
LOC101242365
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.998
LOC100178444
Microtubule-associated proteins 1A/1B light chain 3B-like.
   
 0.955
LOC101243041
Autophagy_act_C domain-containing protein.
    
 0.939
LOC100186746
Autophagy-related protein 3.
    
 0.939
atg5
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.875
LOC100175499
WD_REPEATS_REGION domain-containing protein.
     
 0.855
F6RGX1_CIOIN
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.835
LOC100176463
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
    
 0.816
LOC100185384
ubiquitin-60S ribosomal protein L40.
    
 0.798
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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