STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E(spl)/hairy-bUncharacterized protein. (333 aa)    
Predicted Functional Partners:
groucho1
Groucho.
    
 0.557
groucho2
Uncharacterized protein.
    
 0.557
F6YH17_CIOIN
BHLH domain-containing protein.
   
 
 0.518
LOC100175446
Uncharacterized protein.
    
 
 0.514
LOC100181568
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
   0.459
LOC100181596
Probable nuclear transport factor 2.
    
   0.459
su(h)
Suppressor of hairless homolog; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional expression of Brachyury, suggesting that it participates in notochord differentiation.
   
 0.447
F7B5L6_CIOIN
Uncharacterized protein.
    
 0.439
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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