STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6Z0U1_CIOINDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (380 aa)    
Predicted Functional Partners:
H2XTF1_CIOIN
Mevalonate kinase.
 
 
 0.995
F6SSS9_CIOIN
Nudix hydrolase domain-containing protein.
  
 
 0.994
F6QHP8_CIOIN
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 0.990
H2XW59_CIOIN
Uncharacterized protein.
   
 
 0.975
LOC100175295
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
 
 
 0.882
LOC100182577
RUS1 family protein C16orf58 homolog.
 
      0.875
F6VZQ1_CIOIN
FMN hydroxy acid dehydrogenase domain-containing protein.
    
 0.834
F6SZD3_CIOIN
FMN hydroxy acid dehydrogenase domain-containing protein.
    
 0.834
LOC100175803
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 0.802
LOC113474070
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 0.802
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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