Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100175572Caspase-3-like isoform X1; Belongs to the peptidase C14A family. (375 aa)    
Predicted Functional Partners:
LOC100184308
Centromere protein N-like.
   
 0.814
LOC100179605
Centromere protein M-like.
   
 0.791
LOC100184944
Centromere protein I-like isoform X1.
   
 0.783
LOC104265505
Uncharacterized protein.
   
 0.722
LOC100184986
Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 0.694
LOC100185873-2
Centromere protein S-like isoform X2.
   
 0.662
H2Y1S8_CIOIN
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
  
0.567
H2Y1Q5_CIOIN
SAP domain-containing protein.
    
 0.552
F6RC10_CIOIN
Uncharacterized protein.
   
 0.547
F6R6F3_CIOIN
Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 0.527
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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