Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rcl2Rac and Cdc42-like 2 protein isoform X1. (192 aa)    
Predicted Functional Partners:
Jnk
Mitogen-activated protein kinase.
    
 0.959
F6UKS5_CIOIN
Uncharacterized protein; Belongs to the DOCK family.
   
 0.950
F7B6Z2_CIOIN
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.935
F7BLX1_CIOIN
Uncharacterized protein.
    
  0.930
LOC100182079
PTB domain-containing engulfment adapter protein 1 isoform X1.
    
 0.916
H2Y217_CIOIN
Uncharacterized protein.
    
 0.911
H2XNI5_CIOIN
Ig-like domain-containing protein.
    
 0.866
H2XVQ2_CIOIN
Uncharacterized protein.
    
 0.842
H2XJQ6_CIOIN
PH domain-containing protein.
    
 0.742
H2XVV8_CIOIN
DH domain-containing protein.
    
 0.742
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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