Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100184688Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (438 aa)    
Predicted Functional Partners:
F6SNC6_CIOIN
AdoHcyase_NAD domain-containing protein; Belongs to the adenosylhomocysteinase family.
  
 
 
0.973
LOC100179361
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.969
F6Z9I2_CIOIN
CBS domain-containing protein.
  
 0.965
LOC100182838
Betaine--homocysteine S-methyltransferase 1-like.
  
 
 0.960
F7BDU0_CIOIN
Hcy-binding domain-containing protein.
  
 
 0.960
F7AUB9_CIOIN
Hcy-binding domain-containing protein.
  
 
 0.960
F6PRN9_CIOIN
Uncharacterized protein.
    
   0.953
LOC100187163
Ankyrin repeat domain-containing protein 40-like.
    
   0.952
F6XC87_CIOIN
Hcy-binding domain-containing protein.
  
 
 0.950
F6UMT8_CIOIN
Uncharacterized protein.
  
 0.939
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (14%) [HD]