Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
F6ZHS2_CIOINUncharacterized protein. (484 aa)    
Predicted Functional Partners:
LOC100175299
Endonuclease.
    
 
 0.932
LOC100183112
Mitochondrial intermembrane space import and assembly protein 40-A-like isoform X2.
    
 
 0.920
LOC100181027
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
   
   0.910
F7AVB6_CIOIN
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.821
F6WR85_CIOIN
Dihydrolipoyl dehydrogenase.
  
 0.781
LOC100184688
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
   
 
 0.744
LOC100184986
Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
  
 
 0.684
LOC100183957
Thioredoxin; Belongs to the thioredoxin family.
   
 
 0.673
LOC100181030
Thioredoxin; Belongs to the thioredoxin family.
   
 
 0.673
H2XVU3_CIOIN
Uncharacterized protein.
      
 0.644
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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