pax2/5/8-b protein (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

pax2/5/8-b

Paired domain-containing protein. (1284 aa)

Predicted Functional Partners:

LOC779004

0.794

F6UD40_CIOIN

0.787

gsc

0.774

F6W2W8_CIOIN

0.769

H2XYZ0_CIOIN

0.768

F6VVA7_CIOIN

0.714

Gataa

0.689

otx2

0.655

F6Y9D9_CIOIN

0.647

LOC778588

0.598

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6UD40_CIOIN	F6VVA7_CIOIN	ENSCINP00000017521	ENSCINP00000012025	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox domain-containing protein.	0.927
F6UD40_CIOIN	otx2	ENSCINP00000017521	ENSCINP00000031453	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Transcription factor protein.	0.427
F6UD40_CIOIN	pax2/5/8-b	ENSCINP00000017521	ENSCINP00000012344	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Paired domain-containing protein.	0.787
F6VVA7_CIOIN	F6UD40_CIOIN	ENSCINP00000012025	ENSCINP00000017521	Homeobox domain-containing protein.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.927
F6VVA7_CIOIN	H2XYZ0_CIOIN	ENSCINP00000012025	ENSCINP00000034874	Homeobox domain-containing protein.	Uncharacterized protein.	0.727
F6VVA7_CIOIN	LOC778588	ENSCINP00000012025	ENSCINP00000036336	Homeobox domain-containing protein.	Transcription factor protein.	0.436
F6VVA7_CIOIN	otx2	ENSCINP00000012025	ENSCINP00000031453	Homeobox domain-containing protein.	Transcription factor protein.	0.698
F6VVA7_CIOIN	pax2/5/8-b	ENSCINP00000012025	ENSCINP00000012344	Homeobox domain-containing protein.	Paired domain-containing protein.	0.714
F6W2W8_CIOIN	Gataa	ENSCINP00000004611	ENSCINP00000009159	Runt domain-containing protein.	Uncharacterized protein.	0.887
F6W2W8_CIOIN	LOC779004	ENSCINP00000004611	ENSCINP00000027906	Runt domain-containing protein.	Transcription factor protein.	0.936
F6W2W8_CIOIN	pax2/5/8-b	ENSCINP00000004611	ENSCINP00000012344	Runt domain-containing protein.	Paired domain-containing protein.	0.769
F6Y9D9_CIOIN	pax2/5/8-b	ENSCINP00000019328	ENSCINP00000012344	Uncharacterized protein.	Paired domain-containing protein.	0.647
Gataa	F6W2W8_CIOIN	ENSCINP00000009159	ENSCINP00000004611	Uncharacterized protein.	Runt domain-containing protein.	0.887
Gataa	H2XYZ0_CIOIN	ENSCINP00000009159	ENSCINP00000034874	Uncharacterized protein.	Uncharacterized protein.	0.402
Gataa	LOC778588	ENSCINP00000009159	ENSCINP00000036336	Uncharacterized protein.	Transcription factor protein.	0.749
Gataa	LOC779004	ENSCINP00000009159	ENSCINP00000027906	Uncharacterized protein.	Transcription factor protein.	0.775
Gataa	otx2	ENSCINP00000009159	ENSCINP00000031453	Uncharacterized protein.	Transcription factor protein.	0.581
Gataa	pax2/5/8-b	ENSCINP00000009159	ENSCINP00000012344	Uncharacterized protein.	Paired domain-containing protein.	0.689
H2XYZ0_CIOIN	F6VVA7_CIOIN	ENSCINP00000034874	ENSCINP00000012025	Uncharacterized protein.	Homeobox domain-containing protein.	0.727
H2XYZ0_CIOIN	Gataa	ENSCINP00000034874	ENSCINP00000009159	Uncharacterized protein.	Uncharacterized protein.	0.402