STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6V519_CIOINUncharacterized protein. (1136 aa)    
Predicted Functional Partners:
F6Z6J2_CIOIN
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
   
 
 0.952
LOC100181207
FAD-binding PCMH-type domain-containing protein.
  
  
 
0.915
F6U0U0_CIOIN
Uncharacterized protein.
     
 0.907
H2XZF5_CIOIN
Uncharacterized protein.
     
 0.907
LOC100181350
Uncharacterized protein.
  
  
 
0.901
LOC100178002
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
      
 0.662
H2XK99_CIOIN
Uncharacterized protein.
 
     0.554
LOC100181703
Probable imidazolonepropionase.
  
 
 0.499
F7ASW5_CIOIN
PALP domain-containing protein.
  
 
 0.499
MTAP_CIOIN
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
   
 
 0.488
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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