LOC100184385 protein (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC100184385

Serine/threonine-protein kinase SIK2 isoform X2. (970 aa)

Predicted Functional Partners:

LOC100187157

0.893

LOC100184014

0.748

H2XT58_CIOIN

0.665

H2XK39_CIOIN

0.656

F7BJQ5_CIOIN

0.634

F6SA56_CIOIN

0.602

F6PPJ1_CIOIN

0.573

LOC100186064

0.568

F6T957_CIOIN

0.560

LOC100179943

0.548

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PPJ1_CIOIN	F6SA56_CIOIN	ENSCINP00000006222	ENSCINP00000026610	Protein kinase C.	PDZ domain-containing protein.	0.995
F6PPJ1_CIOIN	H2XT58_CIOIN	ENSCINP00000006222	ENSCINP00000032842	Protein kinase C.	KA1 domain-containing protein.	0.649
F6PPJ1_CIOIN	LOC100184385	ENSCINP00000006222	ENSCINP00000012445	Protein kinase C.	Serine/threonine-protein kinase SIK2 isoform X2.	0.573
F6PPJ1_CIOIN	LOC100186064	ENSCINP00000006222	ENSCINP00000008274	Protein kinase C.	Serine/threonine-protein phosphatase.	0.638
F6SA56_CIOIN	F6PPJ1_CIOIN	ENSCINP00000026610	ENSCINP00000006222	PDZ domain-containing protein.	Protein kinase C.	0.995
F6SA56_CIOIN	H2XT58_CIOIN	ENSCINP00000026610	ENSCINP00000032842	PDZ domain-containing protein.	KA1 domain-containing protein.	0.602
F6SA56_CIOIN	LOC100184385	ENSCINP00000026610	ENSCINP00000012445	PDZ domain-containing protein.	Serine/threonine-protein kinase SIK2 isoform X2.	0.602
F6T957_CIOIN	H2XK39_CIOIN	ENSCINP00000015461	ENSCINP00000030021	Uncharacterized protein.	Protein kinase domain-containing protein.	0.503
F6T957_CIOIN	LOC100184014	ENSCINP00000015461	ENSCINP00000014865	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.982
F6T957_CIOIN	LOC100184385	ENSCINP00000015461	ENSCINP00000012445	Uncharacterized protein.	Serine/threonine-protein kinase SIK2 isoform X2.	0.560
F6T957_CIOIN	LOC100186064	ENSCINP00000015461	ENSCINP00000008274	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.999
F6T957_CIOIN	LOC100187157	ENSCINP00000015461	ENSCINP00000014598	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.635
F7BJQ5_CIOIN	H2XT58_CIOIN	ENSCINP00000021185	ENSCINP00000032842	ANK_REP_REGION domain-containing protein.	KA1 domain-containing protein.	0.634
F7BJQ5_CIOIN	LOC100184385	ENSCINP00000021185	ENSCINP00000012445	ANK_REP_REGION domain-containing protein.	Serine/threonine-protein kinase SIK2 isoform X2.	0.634
H2XK39_CIOIN	F6T957_CIOIN	ENSCINP00000030021	ENSCINP00000015461	Protein kinase domain-containing protein.	Uncharacterized protein.	0.503
H2XK39_CIOIN	H2XT58_CIOIN	ENSCINP00000030021	ENSCINP00000032842	Protein kinase domain-containing protein.	KA1 domain-containing protein.	0.612
H2XK39_CIOIN	LOC100184385	ENSCINP00000030021	ENSCINP00000012445	Protein kinase domain-containing protein.	Serine/threonine-protein kinase SIK2 isoform X2.	0.656
H2XK39_CIOIN	LOC100186064	ENSCINP00000030021	ENSCINP00000008274	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase.	0.691
H2XT58_CIOIN	F6PPJ1_CIOIN	ENSCINP00000032842	ENSCINP00000006222	KA1 domain-containing protein.	Protein kinase C.	0.649
H2XT58_CIOIN	F6SA56_CIOIN	ENSCINP00000032842	ENSCINP00000026610	KA1 domain-containing protein.	PDZ domain-containing protein.	0.602