Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100181970E3 ubiquitin-protein ligase ZNRF2. (217 aa)    
Predicted Functional Partners:
LOC100184240
Ubiquitin-conjugating enzyme E2 35-like isoform X2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.931
zf(ring)-26
Zinc finger protein isoform X2.
      
 0.719
F6TDS0_CIOIN
Uncharacterized protein.
      
 0.694
calx
Calaxin.
      
 0.675
H2XN19_CIOIN
ARL2_Bind_BART domain-containing protein.
      
 0.667
LOC100181090
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
      
 0.538
H2XNY4_CIOIN
EAF domain-containing protein.
      
 0.517
F6ZP18_CIOIN
Uncharacterized protein.
      
 0.511
r27a
R27a protein isoform X1.
    
  0.497
LOC100182633
Peptidylprolyl isomerase.
      
 0.497
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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